What is Parkinson's Disease: A Comprehensive Insight
Parkinson's Disease ( PD ) is a progressive neurodegenerative disorder that predominantly affects movement. It develops gradually, often starting with subtle tremors or a slight stiffness in the limbs. As the condition advances, individuals may experience a wide array of symptoms that significantly impact their daily lives. The Mechanism Behind Parkinson's Disease Dopamine Deficiency and Neural Implications The hallmark characteristic of PD lies in the deterioration of dopamine-producing neurons in the substantia nigra, a region of the brain. Dopamine plays a crucial role in coordinating smooth and controlled muscle movements. When these neurons degenerate, it leads to a deficit in dopamine levels, causing disruptions in motor function. Formation of Lewy Bodies Accumulation of abnormal protein deposits, known as Lewy bodies, within brain cells is closely associated with PD. These deposits contain alpha-synuclein, a protein that clumps together, interfering with normal cellul...